← Pipeline|618-7080

618-7080

Phase 2
Source: Trial-derived·Trials: 2
Modality
Cell Therapy
MOA
CAR-T CD19
Target
MDM2
Pathway
Autophagy
NSCLCACC
Development Pipeline
Preclinical
~Jun 2015
~Sep 2016
Phase 1
~Dec 2016
~Mar 2018
Phase 2
Jun 2018
Oct 2028
Phase 2Current
NCT04797895
2,062 pts·NSCLC
2018-06TBD·Recruiting
NCT08577623
496 pts·ACC
2023-082028-10·Recruiting
2,558 total pts2 indications
Phase 3
NDA/BLA
Approved
CompletedCurrentUpcoming
Catalysts (1)
2028-10-082.5y awayPh2 Data· ACC
Trial Timeline
Q2Q3Q42019Q2Q3Q42020Q2Q3Q42021Q2Q3Q42022Q2Q3Q42023Q2Q3Q42024Q2Q3Q42025Q2Q3Q42026Q2Q3Q42027Q2Q3Q42028Q2Q3Q4
P2
Recruit…
P2
Recruit…
Catalysts
Ph2 Data
2028-10-08 · 2.5y away
ACC
Recruiting|StartCompletionToday
Trials (2)
NCTPhaseIndicationStatusNEP
NCT04797895Phase 2NSCLCRecruiting2062NT-proBNP
NCT08577623Phase 2ACCRecruiting496VA
Competitors (10)
DrugCompanyPhaseTargetMOA
LLY-6079Eli LillyPhase 2MDM2PRMT5i
LLY-3251Eli LillyPhase 2MDM2BiTE
RHH-1546RochePhase 2/3C5CAR-T CD19
DatoglumideAbbVieApprovedCFTRCAR-T CD19
GSK-7987GSKPhase 3MDM2PD-1i
AMG-2752AmgenPreclinicalMDM2WRNi
GIL-2259Gilead SciencesApprovedSMN2CAR-T CD19
REG-3155RegeneronPhase 1/2MDM2PI3Ki
BII-4342BiogenPhase 2/3CGRPCAR-T CD19
SRP-1135SareptaPhase 2/3MDM2PD-L1i