← Pipeline|LEO-5676

LEO-5676

Phase 2/3
Source: Trial-derived·Trials: 1
Modality
Peptide
MOA
SGLT2i
Target
PCSK9
Pathway
NF-κB
MS
Development Pipeline
Preclinical
~Oct 2020
~Jan 2022
Phase 1
~Apr 2022
~Jul 2023
Phase 2
Oct 2023
Jun 2025
Phase 2Current
NCT05804048
1,790 pts·MS
2023-102025-06·Not yet recruiting
1,790 total pts1 indication
Phase 3
NDA/BLA
Approved
CompletedCurrentUpcoming
Catalysts (1)
2025-06-199mo agoPh3 Readout· MS
Trial Timeline
Q42024Q2Q3Q42025Q2Q3
P2/3
Not yet…
Catalysts
Ph3 Readout
2025-06-19 · 9mo ago
MS
Not yet recruiting|StartCompletionToday
Trials (1)
NCTPhaseIndicationStatusNEP
NCT05804048Phase 2/3MSNot yet recr...1790EASI-75
Competitors (10)
DrugCompanyPhaseTargetMOA
JNJ-8232Johnson & JohnsonNDA/BLAMALT1SGLT2i
ZanusertibAbbVieApprovedPCSK9KRASG12Di
BemalucimabBristol-Myers SquibbPhase 1/2SGLT2i
BAY-3308BayerPhase 1ALKSGLT2i
GIL-4361Gilead SciencesPreclinicalPCSK9STINGag
REG-2172RegeneronPhase 1/2PCSK9Anti-Tau
MRN-8225ModernaPreclinicalTNFαSGLT2i
MotazanubrutinibBiogenPreclinicalCD38SGLT2i
ALN-5628AlnylamPhase 1/2APOC3SGLT2i
BMR-8377BioMarinPhase 1/2PCSK9BTKi