← Pipeline|HCM-2035

HCM-2035

Preclinical
Source: Trial-derived·Trials: 1
Modality
mRNA
MOA
CDK2i
Target
C5
Pathway
T-cell
HS
Development Pipeline
Preclinical
Dec 2022
Dec 2026
PreclinicalCurrent
NCT03218944
1,630 pts·HS
2022-122026-12·Completed
1,630 total pts1 indication
Phase 1
Phase 2
Phase 3
NDA/BLA
Approved
CompletedCurrentUpcoming
Catalysts (1)
2026-12-118mo awayInterim· HS
Trial Timeline
2023Q2Q3Q42024Q2Q3Q42025Q2Q3Q42026Q2Q3Q4
Preclinical
Complet…
Catalysts
Interim
2026-12-11 · 8mo away
HS
Completed|StartCompletionToday
Trials (1)
NCTPhaseIndicationStatusNEP
NCT03218944PreclinicalHSCompleted1630MRD
Competitors (10)
DrugCompanyPhaseTargetMOA
PFE-3703PfizerPhase 1/2CDK2CDK2i
LLY-9749Eli LillyPhase 3C5FGFRi
LLY-1184Eli LillyNDA/BLAC5CD3xCD20
RHH-1546RochePhase 2/3C5CAR-T CD19
TirafotisoranRochePhase 2CD38CDK2i
ABB-3951AbbViePhase 2/3TNFαCDK2i
AZN-6870AstraZenecaPhase 2/3EGFRCDK2i
TirasotorasibTakedaNDA/BLAIL-17ACDK2i
BAY-6035BayerPhase 1C5Anti-Aβ
MavuglumideBayerApprovedGLP-1RCDK2i