← Pipeline|Lisosotorasib

Lisosotorasib

Phase 2/3
SOB-2014
By Sobi
Source: Trial-derived·Trials: 1
Modality
Fusion Protein
MOA
HER2
Target
CDK4/6
Pathway
Epigenetic
MCCPVDMD
Development Pipeline
Preclinical
~Jul 2015
~Oct 2016
Phase 1
~Jan 2017
~Apr 2018
Phase 2
Jul 2018
Oct 2025
Phase 2Current
NCT08808600
83 pts·DMD
2018-072025-10·Not yet recruiting
83 total pts1 indication
Phase 3
NDA/BLA
Approved
CompletedCurrentUpcoming
Catalysts (1)
2025-10-056mo agoPh3 Readout· DMD
Trial Timeline
Q3Q42019Q2Q3Q42020Q2Q3Q42021Q2Q3Q42022Q2Q3Q42023Q2Q3Q42024Q2Q3Q42025Q2Q3Q4
P2/3
Not yet…
Catalysts
Ph3 Readout
2025-10-05 · 6mo ago
DMD
Not yet recruiting|StartCompletionToday
Trials (1)
NCTPhaseIndicationStatusNEP
NCT08808600Phase 2/3DMDNot yet recr...83VA
Competitors (10)
DrugCompanyPhaseTargetMOA
PFE-7809PfizerPhase 1DLL3HER2
LLY-8903Eli LillyPreclinicalCD47HER2
SNY-7254SanofiPhase 2CFTRHER2
DatobrutinibSanofiPhase 3HER2
TAK-9344TakedaPhase 3CGRPHER2
MotavorutinibAmgenPhase 3CDK4/6JAK1/2i
RibozanubrutinibRegeneronPhase 1CDK4/6IL-13i
MRN-5715ModernaNDA/BLACDK4/6AuroraAi
VoxaderotideViking TherapeuticsApprovedPD-L1HER2
ElralucimabAxsomePhase 2CDK4/6MDM2i