← Pipeline|MRN-8225

MRN-8225

Preclinical
Source: Trial-derived·Trials: 2
Modality
Vaccine
MOA
SGLT2i
Target
TNFα
Pathway
Wnt
CSUMSRA
Development Pipeline
Preclinical
Aug 2018
Apr 2029
PreclinicalCurrent
NCT03288489
1,267 pts·CSU
2018-11TBD·Terminated
NCT04296448
1,183 pts·MS
2018-082029-04·Recruiting
2,450 total pts2 indications
Phase 1
Phase 2
Phase 3
NDA/BLA
Approved
CompletedCurrentUpcoming
Catalysts (1)
2029-04-203.1y awayInterim· MS
Trial Timeline
Q3Q42019Q2Q3Q42020Q2Q3Q42021Q2Q3Q42022Q2Q3Q42023Q2Q3Q42024Q2Q3Q42025Q2Q3Q42026Q2Q3Q42027Q2Q3Q42028Q2Q3Q42029Q2Q3
Preclinical
Recruit…
Preclinical
Termina…
Catalysts
Interim
2029-04-20 · 3.1y away
MS
RecruitingTerminated|StartCompletionToday
Trials (2)
NCTPhaseIndicationStatusNEP
NCT03288489PreclinicalCSUTerminated1267Biomarker
NCT04296448PreclinicalMSRecruiting1183PANSS
Competitors (10)
DrugCompanyPhaseTargetMOA
JNJ-8232Johnson & JohnsonNDA/BLAMALT1SGLT2i
ABB-3951AbbViePhase 2/3TNFαCDK2i
BemalucimabBristol-Myers SquibbPhase 1/2SGLT2i
BAY-3308BayerPhase 1ALKSGLT2i
GIL-6239Gilead SciencesPhase 2TNFαCGRPant
MotazanubrutinibBiogenPreclinicalCD38SGLT2i
ALN-5628AlnylamPhase 1/2APOC3SGLT2i
SovanaritideArgenxPhase 3TNFαBETi
369-4107Hansoh PharmaPhase 2TNFαSHP2i
VKT-4052Viking TherapeuticsPhase 2/3TNFαWRNi