← Pipeline|PBY-3950

PBY-3950

Phase 2
Source: Trial-derived·Trials: 1
Modality
Gene Therapy
MOA
STINGag
Target
FGFR
Pathway
NF-κB
CSUMMEndometrial Ca
Development Pipeline
Preclinical
~Jan 2021
~Apr 2022
Phase 1
~Jul 2022
~Oct 2023
Phase 2
Jan 2024
Mar 2029
Phase 2Current
NCT04184483
2,007 pts·Endometrial Ca
2024-012029-03·Terminated
2,007 total pts1 indication
Phase 3
NDA/BLA
Approved
CompletedCurrentUpcoming
Catalysts (1)
2029-03-243.0y awayPh2 Data· Endometrial Ca
Trial Timeline
2024Q2Q3Q42025Q2Q3Q42026Q2Q3Q42027Q2Q3Q42028Q2Q3Q42029Q2
P2
Termina…
Catalysts
Ph2 Data
2029-03-24 · 3.0y away
Endometrial Ca
Terminated|StartCompletionToday
Trials (1)
NCTPhaseIndicationStatusNEP
NCT04184483Phase 2Endometrial CaTerminated20076MWD
Competitors (10)
DrugCompanyPhaseTargetMOA
LLY-1592Eli LillyNDA/BLAFGFRBETi
RHH-5389RochePreclinicalRETSTINGag
DoxarasimodMerck & CoNDA/BLAFGFRKRASG12Di
AZN-7403AstraZenecaPhase 2/3FGFRTNFi
SNY-5894SanofiApprovedCFTRSTINGag
SNY-4496SanofiPhase 2/3CD3STINGag
SNY-5783SanofiPhase 1/2METSTINGag
DSN-1421Daiichi SankyoPhase 3Nectin-4STINGag
GIL-4361Gilead SciencesPreclinicalPCSK9STINGag
CevitinibRegeneronPhase 3FGFRPCSK9i