← Pipeline|EME-6317

EME-6317

Approved
Source: Trial-derived·Trials: 3
Modality
Radioligand
MOA
GLP-1/GIP
Target
SOS1
Pathway
mTOR
MGCrohn'sSCD
Development Pipeline
Preclinical
~Sep 2009
~Dec 2010
Phase 1
~Mar 2011
~Jun 2012
Phase 2
~Sep 2012
~Dec 2013
Phase 3
~Mar 2014
~Jun 2015
NDA/BLA
~Sep 2015
~Dec 2016
Approved
Mar 2017
Dec 2028
ApprovedCurrent
NCT03746415
2,605 pts·SCD
2018-07TBD·Not yet recruiting
NCT07982784
1,588 pts·Crohn's
2023-042028-12·Recruiting
NCT08655545
467 pts·MG
2017-03TBD·Not yet recruiting
4,660 total pts3 indications
CompletedCurrentUpcoming
Catalysts (1)
2028-12-282.7y awayPh3 Readout· Crohn's
Trial Timeline
2017Q2Q3Q42018Q2Q3Q42019Q2Q3Q42020Q2Q3Q42021Q2Q3Q42022Q2Q3Q42023Q2Q3Q42024Q2Q3Q42025Q2Q3Q42026Q2Q3Q42027Q2Q3Q42028Q2Q3Q4
Approved
Not yet…
Approved
Not yet…
Approved
Recruit…
Catalysts
Ph3 Readout
2028-12-28 · 2.7y away
Crohn's
RecruitingNot yet recruiting|StartCompletionToday
Trials (3)
NCTPhaseIndicationStatusNEP
NCT03746415ApprovedSCDNot yet recr...2605DOR
NCT07982784ApprovedCrohn'sRecruiting1588PASI75
NCT08655545ApprovedMGNot yet recr...467PFS
Competitors (10)
DrugCompanyPhaseTargetMOA
ZanuderotideJohnson & JohnsonPhase 2/3TIGITGLP-1/GIP
JNJ-8168Johnson & JohnsonPhase 2/3FLT3GLP-1/GIP
TerarelsinAbbViePreclinicalSOS1SOS1i
RibofutibatinibAstraZenecaPhase 2/3SOS1PCSK9i
AZN-5171AstraZenecaApprovedGLP-1RGLP-1/GIP
VoxacageneGilead SciencesPhase 2/3SOS1TYK2i
SRP-9822SareptaPhase 3SOS1FGFRi
PemiinavolisibSareptaNDA/BLACD47GLP-1/GIP
FixaosocimabTG TherapeuticsPhase 2/3SOS1PI3Ki
ZanurapivirImmunocorePhase 1SOS1PRMT5i