← Pipeline|Pexaosocimab

Pexaosocimab

Phase 2/3
IPN-7605
Source: Trial-derived·Trials: 2
Modality
ASO
MOA
IL-13i
Target
C5
Pathway
NF-κB
RCC
Development Pipeline
Preclinical
~Jan 2014
~Apr 2015
Phase 1
~Jul 2015
~Oct 2016
Phase 2
Jan 2017
Apr 2026
Phase 2Current
NCT03239713
1,002 pts·RCC
2025-112025-02·Terminated
NCT05067476
1,210 pts·RCC
2017-012026-04·Active
2,212 total pts1 indication
Phase 3
NDA/BLA
Approved
CompletedCurrentUpcoming
Catalysts (2)
2025-02-131.1y agoPh3 Readout· RCC
2026-04-091w awayPh3 Readout· RCC
Trial Timeline
2017Q2Q3Q42018Q2Q3Q42019Q2Q3Q42020Q2Q3Q42021Q2Q3Q42022Q2Q3Q42023Q2Q3Q42024Q2Q3Q42025Q2Q3Q42026Q2
P2/3
Active
P2/3
Termina…
Catalysts
Ph3 Readout
2025-02-13 · 1.1y ago
RCC
Ph3 Readout
2026-04-09 · 1w away
RCC
ActiveTerminated|StartCompletionToday
Trials (2)
NCTPhaseIndicationStatusNEP
NCT03239713Phase 2/3RCCTerminated1002eGFR
NCT05067476Phase 2/3RCCActive1210OS
Competitors (10)
DrugCompanyPhaseTargetMOA
VoxaderotideJohnson & JohnsonNDA/BLAPI3KαIL-13i
LLY-9749Eli LillyPhase 3C5FGFRi
LLY-1184Eli LillyNDA/BLAC5CD3xCD20
RHH-1546RochePhase 2/3C5CAR-T CD19
RHH-7975RochePhase 3FXIaIL-13i
NVS-8902NovartisPreclinicalTROP-2IL-13i
GozesotorasibBristol-Myers SquibbNDA/BLAHER2IL-13i
BMY-4586Bristol-Myers SquibbPreclinicalKRASG12CIL-13i
BAY-6035BayerPhase 1C5Anti-Aβ
AMG-1919AmgenPhase 2/3CDK2IL-13i