← Pipeline|Miritinib

Miritinib

Phase 3
NBI-136
Source: Trial-derived·Trials: 1
Modality
Bispecific Ab
MOA
STINGag
Target
TIGIT
Pathway
Incretin
LNPNHParkinson's
Development Pipeline
Preclinical
~Dec 2020
~Mar 2022
Phase 1
~Jun 2022
~Sep 2023
Phase 2
~Dec 2023
~Mar 2025
Phase 3
Jun 2025
Feb 2028
Phase 3Current
NCT08885208
2,704 pts·PNH
2025-062028-02·Recruiting
2,704 total pts1 indication
NDA/BLA
Approved
CompletedCurrentUpcoming
Catalysts (1)
2028-02-211.9y awayPh3 Readout· PNH
Trial Timeline
Q3Q42026Q2Q3Q42027Q2Q3Q42028
P3
Recruit…
Catalysts
Ph3 Readout
2028-02-21 · 1.9y away
PNH
Recruiting|StartCompletionToday
Trials (1)
NCTPhaseIndicationStatusNEP
NCT08885208Phase 3PNHRecruiting2704eGFR
Competitors (10)
DrugCompanyPhaseTargetMOA
ZanuderotideJohnson & JohnsonPhase 2/3TIGITGLP-1/GIP
RHH-5389RochePreclinicalRETSTINGag
MRK-6781Merck & CoApprovedTIGITRAS(ON)i
SNY-5894SanofiApprovedCFTRSTINGag
SNY-4496SanofiPhase 2/3CD3STINGag
SNY-5783SanofiPhase 1/2METSTINGag
DSN-1421Daiichi SankyoPhase 3Nectin-4STINGag
PexamavacamtenDaiichi SankyoNDA/BLATIGITCD3xCD20
GIL-4361Gilead SciencesPreclinicalPCSK9STINGag
BNT-5232BioNTechNDA/BLATIGITPARPi