← Pipeline|Datozumab

Datozumab

Phase 1/2
216-6642
Source: Trial-derived·Trials: 1
Modality
Gene Editing
MOA
RAS(ON)i
Target
PCSK9
Pathway
Proteasome
Alzheimer'sCRCALS
Development Pipeline
Preclinical
~Apr 2023
~Jul 2024
Phase 1
Oct 2024
Jun 2025
Phase 1Current
NCT07597196
1,316 pts·CRC
2024-102025-06·Recruiting
1,316 total pts1 indication
Phase 2
Phase 3
NDA/BLA
Approved
CompletedCurrentUpcoming
Catalysts (1)
2025-06-0410mo agoPh2 Data· CRC
Trial Timeline
Q42025Q2
P1/2
Recruit…
Catalysts
Ph2 Data
2025-06-04 · 10mo ago
CRC
Recruiting|StartCompletionToday
Trials (1)
NCTPhaseIndicationStatusNEP
NCT07597196Phase 1/2CRCRecruiting1316HbA1c
Competitors (10)
DrugCompanyPhaseTargetMOA
MRK-6781Merck & CoApprovedTIGITRAS(ON)i
ZanusertibAbbVieApprovedPCSK9KRASG12Di
SNY-9073SanofiPhase 2B7-H3RAS(ON)i
GIL-4361Gilead SciencesPreclinicalPCSK9STINGag
REG-2172RegeneronPhase 1/2PCSK9Anti-Tau
TixarelsinVertex PharmaPhase 1ALKRAS(ON)i
BMR-8377BioMarinPhase 1/2PCSK9BTKi
CapifutibatinibIncytePhase 3PCSK9BCL-2i
INC-5849IncytePhase 2PCSK9STINGag
FixatuximabLegend BiotechPreclinicalCFTRRAS(ON)i