← Pipeline|Sotosacituzumab

Sotosacituzumab

Phase 1
VRT-4359
Source: Trial-derived·Trials: 2
Modality
Cell Therapy
MOA
TYK2i
Target
MET
Pathway
Wnt
ALL
Development Pipeline
Preclinical
~Jan 2017
~Apr 2018
Phase 1
Jul 2018
Oct 2027
Phase 1Current
NCT07139539
405 pts·ALL
2025-04TBD·Recruiting
NCT06020175
1,234 pts·ALL
2018-072027-10·Recruiting
1,639 total pts1 indication
Phase 2
Phase 3
NDA/BLA
Approved
CompletedCurrentUpcoming
Catalysts (1)
2027-10-071.5y awayInterim· ALL
Trial Timeline
Q3Q42019Q2Q3Q42020Q2Q3Q42021Q2Q3Q42022Q2Q3Q42023Q2Q3Q42024Q2Q3Q42025Q2Q3Q42026Q2Q3Q42027Q2Q3Q4
P1
Recruit…
P1
Recruit…
Catalysts
Interim
2027-10-07 · 1.5y away
ALL
Recruiting|StartCompletionToday
Trials (2)
NCTPhaseIndicationStatusNEP
NCT07139539Phase 1ALLRecruiting405EASI-75
NCT06020175Phase 1ALLRecruiting1234DOR
Competitors (10)
DrugCompanyPhaseTargetMOA
NidasacituzumabEli LillyApprovedCFTRTYK2i
LisonaritideEli LillyPhase 3IL-13TYK2i
MRK-2473Merck & CoPhase 1/2Nectin-4TYK2i
ZorisotorasibAstraZenecaPhase 1WRNTYK2i
SNY-8628SanofiNDA/BLAB7-H3TYK2i
SNY-5783SanofiPhase 1/2METSTINGag
VoxacageneGilead SciencesPhase 2/3SOS1TYK2i
SotorapivirModernaApprovedFLT3TYK2i
OlpainavolisibModernaPhase 1MeninTYK2i
ARG-4339ArgenxPhase 2BCL-2TYK2i