← Pipeline|BCY-3228

BCY-3228

Preclinical
Source: Trial-derived·Trials: 2
Modality
Peptide
MOA
CDK2i
Target
GIP-R
Pathway
NF-κB
Meso
Development Pipeline
Preclinical
Apr 2018
Feb 2028
PreclinicalCurrent
NCT07964391
2,632 pts·Meso
2018-042025-06·Not yet recruiting
NCT03142376
2,152 pts·Meso
2021-042028-02·Completed
4,784 total pts1 indication
Phase 1
Phase 2
Phase 3
NDA/BLA
Approved
CompletedCurrentUpcoming
Catalysts (2)
2025-06-0610mo agoInterim· Meso
2028-02-051.9y awayInterim· Meso
Trial Timeline
Q2Q3Q42019Q2Q3Q42020Q2Q3Q42021Q2Q3Q42022Q2Q3Q42023Q2Q3Q42024Q2Q3Q42025Q2Q3Q42026Q2Q3Q42027Q2Q3Q42028Q2
Preclinical
Not yet…
Preclinical
Complet…
Catalysts
Interim
2025-06-06 · 10mo ago
Meso
Interim
2028-02-05 · 1.9y away
Meso
CompletedNot yet recruiting|StartCompletionToday
Trials (2)
NCTPhaseIndicationStatusNEP
NCT07964391PreclinicalMesoNot yet recr...2632EDSS
NCT03142376PreclinicalMesoCompleted2152ORR
Competitors (10)
DrugCompanyPhaseTargetMOA
PFE-3703PfizerPhase 1/2CDK2CDK2i
JNJ-5094Johnson & JohnsonPhase 2/3GIP-REGFRi
RHH-3592RochePhase 1/2GIP-RBCL-2i
TirafotisoranRochePhase 2CD38CDK2i
ABB-3951AbbViePhase 2/3TNFαCDK2i
AZN-6870AstraZenecaPhase 2/3EGFRCDK2i
AZN-5978AstraZenecaPhase 2/3GIP-RAHRant
IvotuximabGSKNDA/BLAGIP-RKRASG12Di
TirasotorasibTakedaNDA/BLAIL-17ACDK2i
MavuglumideBayerApprovedGLP-1RCDK2i