← Pipeline|Semalucimab

Semalucimab

Phase 3
ZEA-1183
Source: Trial-derived·Trials: 2
Modality
ADC
MOA
STINGag
Target
BET
Pathway
Tau
DMD
Development Pipeline
Preclinical
~Jan 2013
~Apr 2014
Phase 1
~Jul 2014
~Oct 2015
Phase 2
~Jan 2016
~Apr 2017
Phase 3
Jul 2017
Nov 2030
Phase 3Current
NCT07587815
775 pts·DMD
2017-072028-10·Terminated
NCT06560504
244 pts·DMD
2024-052030-11·Terminated
1,019 total pts1 indication
NDA/BLA
Approved
CompletedCurrentUpcoming
Catalysts (2)
2028-10-022.5y awayPh3 Readout· DMD
2030-11-034.6y awayPh3 Readout· DMD
Trial Timeline
Q2Q3Q42018Q2Q3Q42019Q2Q3Q42020Q2Q3Q42021Q2Q3Q42022Q2Q3Q42023Q2Q3Q42024Q2Q3Q42025Q2Q3Q42026Q2Q3Q42027Q2Q3Q42028Q2Q3Q42029Q2Q3Q42030Q2Q3Q4
P3
Termina…
P3
Termina…
Catalysts
Ph3 Readout
2028-10-02 · 2.5y away
DMD
Ph3 Readout
2030-11-03 · 4.6y away
DMD
Terminated|StartCompletionToday
Trials (2)
NCTPhaseIndicationStatusNEP
NCT07587815Phase 3DMDTerminated775DAS28
NCT06560504Phase 3DMDTerminated244Biomarker
Competitors (10)
DrugCompanyPhaseTargetMOA
PFE-5767PfizerPhase 1/2BETCDK4/6i
RHH-1969RocheApprovedBETCDK4/6i
RHH-5389RochePreclinicalRETSTINGag
NVS-5439NovartisPreclinicalBETAnti-Tau
IvocapivasertibBristol-Myers SquibbPhase 1BETCDK4/6i
SNY-5894SanofiApprovedCFTRSTINGag
SNY-4496SanofiPhase 2/3CD3STINGag
SNY-5783SanofiPhase 1/2METSTINGag
DSN-1421Daiichi SankyoPhase 3Nectin-4STINGag
GIL-4361Gilead SciencesPreclinicalPCSK9STINGag