← Pipeline|ALK-3993

ALK-3993

Phase 3
Source: Trial-derived·Trials: 1
Modality
Bispecific Ab
MOA
GLP-1/GIP
Target
SOS1
Pathway
JAK/STAT
MigraineNarcolepsyLGS
Development Pipeline
Preclinical
~Nov 2012
~Feb 2014
Phase 1
~May 2014
~Aug 2015
Phase 2
~Nov 2015
~Feb 2017
Phase 3
May 2017
Apr 2026
Phase 3Current
NCT06453865
1,643 pts·LGS
2017-052026-04·Active
1,643 total pts1 indication
NDA/BLA
Approved
CompletedCurrentUpcoming
Catalysts (1)
2026-04-162w awayPh3 Readout· LGS
Trial Timeline
Q2Q3Q42018Q2Q3Q42019Q2Q3Q42020Q2Q3Q42021Q2Q3Q42022Q2Q3Q42023Q2Q3Q42024Q2Q3Q42025Q2Q3Q42026Q2
P3
Active
Catalysts
Ph3 Readout
2026-04-16 · 2w away
LGS
Active|StartCompletionToday
Trials (1)
NCTPhaseIndicationStatusNEP
NCT06453865Phase 3LGSActive1643Safety
Competitors (10)
DrugCompanyPhaseTargetMOA
ZanuderotideJohnson & JohnsonPhase 2/3TIGITGLP-1/GIP
JNJ-8168Johnson & JohnsonPhase 2/3FLT3GLP-1/GIP
TerarelsinAbbViePreclinicalSOS1SOS1i
RibofutibatinibAstraZenecaPhase 2/3SOS1PCSK9i
AZN-5171AstraZenecaApprovedGLP-1RGLP-1/GIP
VoxacageneGilead SciencesPhase 2/3SOS1TYK2i
SRP-9822SareptaPhase 3SOS1FGFRi
PemiinavolisibSareptaNDA/BLACD47GLP-1/GIP
FixaosocimabTG TherapeuticsPhase 2/3SOS1PI3Ki
ZanurapivirImmunocorePhase 1SOS1PRMT5i