← Pipeline|DES-7076

DES-7076

Phase 2
Source: Trial-derived·Trials: 2
Modality
siRNA
MOA
GLP-1/GIP
Target
CD123
Pathway
Incretin
Urothelial Ca
Development Pipeline
Preclinical
~Jan 2020
~Apr 2021
Phase 1
~Jul 2021
~Oct 2022
Phase 2
Jan 2023
Jul 2025
Phase 2Current
NCT05936888
2,618 pts·Urothelial Ca
2023-012025-07·Recruiting
NCT03229530
490 pts·Urothelial Ca
2025-05TBD·Recruiting
3,108 total pts1 indication
Phase 3
NDA/BLA
Approved
CompletedCurrentUpcoming
Catalysts (2)
2025-07-129mo agoPh2 Data· Urothelial Ca
2025-07-149mo agoConference· Urothelial Ca
Trial Timeline
2023Q2Q3Q42024Q2Q3Q42025Q2Q3
P2
Recruit…
P2
Recruit…
Catalysts
Ph2 Data
2025-07-12 · 9mo ago
Urothelial Ca
Conference
2025-07-14 · 9mo ago
Urothelial Ca
Recruiting|StartCompletionToday
Trials (2)
NCTPhaseIndicationStatusNEP
NCT05936888Phase 2Urothelial CaRecruiting2618VA
NCT03229530Phase 2Urothelial CaRecruiting490ACR20
Competitors (10)
DrugCompanyPhaseTargetMOA
ZanuderotideJohnson & JohnsonPhase 2/3TIGITGLP-1/GIP
JNJ-8168Johnson & JohnsonPhase 2/3FLT3GLP-1/GIP
AZN-5171AstraZenecaApprovedGLP-1RGLP-1/GIP
REG-7737RegeneronPreclinicalCD123WRNi
PemiinavolisibSareptaNDA/BLACD47GLP-1/GIP
IvotuximabMadrigal PharmaPhase 2CD123CFTRmod
ZorizumabBeamApprovedCD123AuroraAi
BEA-4274BeamPhase 1/2ALKGLP-1/GIP
AdagralucimabCaribou BioNDA/BLACD123RAS(ON)i
PST-2276PoseidaApprovedGLP-1/GIP