← Pipeline|Fixalucimab

Fixalucimab

NDA/BLA
GNF-9068
Source: Trial-derived·Trials: 2
Modality
Small Molecule
MOA
GLP-1/GIP
Target
HER2
Pathway
Wnt
CMLGISTPV
Development Pipeline
Preclinical
~Jan 2013
~Apr 2014
Phase 1
~Jul 2014
~Oct 2015
Phase 2
~Jan 2016
~Apr 2017
Phase 3
~Jul 2017
~Oct 2018
NDA/BLA
Jan 2019
Oct 2030
NDA/BLACurrent
NCT06572007
2,199 pts·PV
2019-012030-06·Recruiting
NCT05610478
738 pts·GIST
2019-092030-10·Active
2,937 total pts2 indications
Approved
CompletedCurrentUpcoming
Catalysts (2)
2030-06-114.2y awayPh3 Readout· PV
2030-10-124.5y awayPh3 Readout· GIST
Trial Timeline
2019Q2Q3Q42020Q2Q3Q42021Q2Q3Q42022Q2Q3Q42023Q2Q3Q42024Q2Q3Q42025Q2Q3Q42026Q2Q3Q42027Q2Q3Q42028Q2Q3Q42029Q2Q3Q42030Q2Q3Q4
NDA/BLA
Recruit…
NDA/BLA
Active
Catalysts
Ph3 Readout
2030-06-11 · 4.2y away
PV
Ph3 Readout
2030-10-12 · 4.5y away
GIST
RecruitingActive|StartCompletionToday
Trials (2)
NCTPhaseIndicationStatusNEP
NCT06572007NDA/BLAPVRecruiting2199ORR
NCT05610478NDA/BLAGISTActive738UPDRS
Competitors (10)
DrugCompanyPhaseTargetMOA
ZanuderotideJohnson & JohnsonPhase 2/3TIGITGLP-1/GIP
JNJ-8168Johnson & JohnsonPhase 2/3FLT3GLP-1/GIP
AZN-5171AstraZenecaApprovedGLP-1RGLP-1/GIP
GozesotorasibBristol-Myers SquibbNDA/BLAHER2IL-13i
VRT-4938Vertex PharmaPreclinicalHER2CDK4/6i
PemiinavolisibSareptaNDA/BLACD47GLP-1/GIP
ROI-9675Roivant SciencesNDA/BLAHER2USP1i
BEA-4274BeamPhase 1/2ALKGLP-1/GIP
ELV-1411EnlivenNDA/BLAHER2Cl18.2
PST-2276PoseidaApprovedGLP-1/GIP