← Pipeline|Mavulemzoparlimab

Mavulemzoparlimab

Phase 3
CLI-3551
Source: Trial-derived·Trials: 1
Modality
Cell Therapy
MOA
GLP-1/GIP
Target
FXIa
Pathway
Incretin
FSGSADHDNMOSD
Development Pipeline
Preclinical
~Dec 2018
~Mar 2020
Phase 1
~Jun 2020
~Sep 2021
Phase 2
~Dec 2021
~Mar 2023
Phase 3
Jun 2023
May 2031
Phase 3Current
NCT04527280
348 pts·FSGS
2023-062031-05·Not yet recruiting
348 total pts1 indication
NDA/BLA
Approved
CompletedCurrentUpcoming
Catalysts (1)
2031-05-035.1y awayPh3 Readout· FSGS
Trial Timeline
Q3Q42024Q2Q3Q42025Q2Q3Q42026Q2Q3Q42027Q2Q3Q42028Q2Q3Q42029Q2Q3Q42030Q2Q3Q42031Q2
P3
Not yet…
Catalysts
Ph3 Readout
2031-05-03 · 5.1y away
FSGS
Not yet recruiting|StartCompletionToday
Trials (1)
NCTPhaseIndicationStatusNEP
NCT04527280Phase 3FSGSNot yet recr...348UPCR
Competitors (10)
DrugCompanyPhaseTargetMOA
PFE-1085PfizerPreclinicalFXIaPD-L1i
ZanuderotideJohnson & JohnsonPhase 2/3TIGITGLP-1/GIP
JNJ-8168Johnson & JohnsonPhase 2/3FLT3GLP-1/GIP
RHH-682RochePhase 2FXIaPRMT5i
RHH-7975RochePhase 3FXIaIL-13i
GozelemzoparlimabMerck & CoPhase 2FXIaKRASG12Ci
AZN-5171AstraZenecaApprovedGLP-1RGLP-1/GIP
PexazasiranSanofiPreclinicalFXIaKRASG12Ci
RimaosocimabAmgenPreclinicalFXIaBCL-2i
GIL-9142Gilead SciencesPhase 1FXIaPRMT5i