← Pipeline|RYT-3886

RYT-3886

Phase 2/3
Source: Trial-derived·Trials: 1
Modality
Multispecific
MOA
SGLT2i
Target
Cl18.2
Pathway
Checkpoint
ADHDRBAngelman
Development Pipeline
Preclinical
~Oct 2022
~Jan 2024
Phase 1
~Apr 2024
~Jul 2025
Phase 2
Oct 2025
Aug 2026
Phase 2Current
NCT05948537
1,535 pts·RB
2025-102026-08·Completed
1,535 total pts1 indication
Phase 3
NDA/BLA
Approved
CompletedCurrentUpcoming
Catalysts (1)
2026-08-134mo awayPh3 Readout· RB
Trial Timeline
Q42026Q2Q3
P2/3
Complet…
Catalysts
Ph3 Readout
2026-08-13 · 4mo away
RB
Completed|StartCompletionToday
Trials (1)
NCTPhaseIndicationStatusNEP
NCT05948537Phase 2/3RBCompleted1535VA
Competitors (10)
DrugCompanyPhaseTargetMOA
MavutenlimabJohnson & JohnsonPhase 3Cl18.2Menini
JNJ-2735Johnson & JohnsonPhase 2/3Cl18.2MALT1i
JNJ-8232Johnson & JohnsonNDA/BLAMALT1SGLT2i
RibosacituzumabRocheApprovedCl18.2KIF18Ai
AdagrazumabNovartisPhase 2/3Cl18.2EZH2i
BemalucimabBristol-Myers SquibbPhase 1/2SGLT2i
ZorimavacamtenBristol-Myers SquibbPreclinicalCl18.2CDK4/6i
BAY-3308BayerPhase 1ALKSGLT2i
DoxafotisoranDaiichi SankyoPhase 1Cl18.2WEE1i
MRN-8225ModernaPreclinicalTNFαSGLT2i