← Pipeline|BTA-1886

BTA-1886

Phase 1
Source: Trial-derived·Trials: 1
Modality
Degrader
MOA
CD3xCD20
Target
FXIa
Pathway
Sphingolipid
ThymomaHuntington's
Development Pipeline
Preclinical
~Dec 2019
~Mar 2021
Phase 1
Jun 2021
May 2029
Phase 1Current
NCT05877527
2,649 pts·Thymoma
2021-062029-05·Not yet recruiting
2,649 total pts1 indication
Phase 2
Phase 3
NDA/BLA
Approved
CompletedCurrentUpcoming
Catalysts (1)
2029-05-273.2y awayInterim· Thymoma
Trial Timeline
Q3Q42022Q2Q3Q42023Q2Q3Q42024Q2Q3Q42025Q2Q3Q42026Q2Q3Q42027Q2Q3Q42028Q2Q3Q42029Q2Q3
P1
Not yet…
Catalysts
Interim
2029-05-27 · 3.2y away
Thymoma
Not yet recruiting|StartCompletionToday
Trials (1)
NCTPhaseIndicationStatusNEP
NCT05877527Phase 1ThymomaNot yet recr...2649NT-proBNP
Competitors (10)
DrugCompanyPhaseTargetMOA
PFE-1085PfizerPreclinicalFXIaPD-L1i
LLY-1184Eli LillyNDA/BLAC5CD3xCD20
RHH-682RochePhase 2FXIaPRMT5i
RHH-7975RochePhase 3FXIaIL-13i
ZanuderotideNovartisPhase 1/2VEGFCD3xCD20
GozelemzoparlimabMerck & CoPhase 2FXIaKRASG12Ci
PexazasiranSanofiPreclinicalFXIaKRASG12Ci
NVO-1361Novo NordiskPhase 3CD38CD3xCD20
ZorizanubrutinibNovo NordiskPhase 1BTKCD3xCD20
PexamavacamtenDaiichi SankyoNDA/BLATIGITCD3xCD20