← Pipeline|Voxasertib

Voxasertib

Phase 3
KMD-760
Source: Trial-derived·Trials: 2
Modality
ADC
MOA
FGFRi
Target
MDM2
Pathway
mTOR
Melanoma
Development Pipeline
Preclinical
~Apr 2017
~Jul 2018
Phase 1
~Oct 2018
~Jan 2020
Phase 2
~Apr 2020
~Jul 2021
Phase 3
Oct 2021
May 2025
Phase 3Current
NCT04465756
1,984 pts·Melanoma
2023-092025-05·Recruiting
NCT05893354
769 pts·Melanoma
2021-10TBD·Active
2,753 total pts1 indication
NDA/BLA
Approved
CompletedCurrentUpcoming
Catalysts (1)
2025-05-2210mo agoPh3 Readout· Melanoma
Trial Timeline
Q42022Q2Q3Q42023Q2Q3Q42024Q2Q3Q42025Q2
P3
Active
P3
Recruit…
Catalysts
Ph3 Readout
2025-05-22 · 10mo ago
Melanoma
RecruitingActive|StartCompletionToday
Trials (2)
NCTPhaseIndicationStatusNEP
NCT04465756Phase 3MelanomaRecruiting1984OS
NCT05893354Phase 3MelanomaActive769eGFR
Competitors (10)
DrugCompanyPhaseTargetMOA
LLY-6079Eli LillyPhase 2MDM2PRMT5i
LLY-9749Eli LillyPhase 3C5FGFRi
LLY-1956Eli LillyPhase 1/2BCMAFGFRi
LLY-3251Eli LillyPhase 2MDM2BiTE
GSK-7987GSKPhase 3MDM2PD-1i
AMG-2752AmgenPreclinicalMDM2WRNi
REG-3155RegeneronPhase 1/2MDM2PI3Ki
SRP-9822SareptaPhase 3SOS1FGFRi
SRP-1135SareptaPhase 2/3MDM2PD-L1i
RimainavolisibIlluminaPhase 2PD-1FGFRi