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← Pipeline|CRV-1020

CRV-1020

Approved
By CervoMed
Source: Trial-derived·Trials: 1
Modality
ADC
MOA
USP1i
Target
CDK4/6
Pathway
Hedgehog
PSPADPKDDMD
Development Pipeline
Preclinical
~Jun 2014
→ ~Sep 2015
Phase 1
~Dec 2015
→ ~Mar 2017
Phase 2
~Jun 2017
→ ~Sep 2018
Phase 3
~Dec 2018
→ ~Mar 2020
NDA/BLA
~Jun 2020
→ ~Sep 2021
Approved
Dec 2021
ApprovedCurrent
NCT07787002
1,733 pts·PSP
2021-12→TBD·Terminated
1,733 total pts1 indication
CompletedCurrentUpcoming
Trial Timeline
Approved
Termina…
Terminated|StartCompletionToday
Trials (1)
NCTPhaseIndicationStatusNEP
NCT07787002ApprovedPSPTerminated1733ORR
Competitors (10)
DrugCompanyPhaseTargetMOA
SNY-2934SanofiPhase 3KRASG12DUSP1i
AMG-9052AmgenPhase 2/3CDK2USP1i
MotavorutinibAmgenPhase 3CDK4/6JAK1/2i
RibozanubrutinibRegeneronPhase 1CDK4/6IL-13i
DatozumabRegeneronPhase 1B7-H3USP1i
MRN-5715ModernaNDA/BLACDK4/6AuroraAi
GMA-729GenmabPhase 2BCL-2USP1i
PexanaritideInnovent BioPreclinicalSGLT2USP1i
ROI-9675Roivant SciencesNDA/BLAHER2USP1i
ElralucimabAxsomePhase 2CDK4/6MDM2i