← Pipeline|ISO-9327

ISO-9327

Phase 1
Source: Trial-derived·Trials: 1
Modality
Radioligand
MOA
RAS(ON)i
Target
KRASG12C
Pathway
Innate Imm
NBMSWet AMD
Development Pipeline
Preclinical
~Sep 2023
~Dec 2024
Phase 1
Mar 2025
Sep 2029
Phase 1Current
NCT08761665
277 pts·MS
2025-032029-09·Not yet recruiting
277 total pts1 indication
Phase 2
Phase 3
NDA/BLA
Approved
CompletedCurrentUpcoming
Catalysts (1)
2029-09-273.5y awayInterim· MS
Trial Timeline
Q2Q3Q42026Q2Q3Q42027Q2Q3Q42028Q2Q3Q42029Q2Q3Q4
P1
Not yet…
Catalysts
Interim
2029-09-27 · 3.5y away
MS
Not yet recruiting|StartCompletionToday
Trials (1)
NCTPhaseIndicationStatusNEP
NCT08761665Phase 1MSNot yet recr...277MRD
Competitors (10)
DrugCompanyPhaseTargetMOA
JNJ-179Johnson & JohnsonApprovedKRASG12CBETi
MRK-6781Merck & CoApprovedTIGITRAS(ON)i
BMY-4586Bristol-Myers SquibbPreclinicalKRASG12CIL-13i
DoxarapivirBristol-Myers SquibbPhase 3KRASG12CSOS1i
SNY-9073SanofiPhase 2B7-H3RAS(ON)i
AMG-4531AmgenPhase 2/3KRASG12CPRMT5i
REG-8074RegeneronPhase 2/3KRASG12CCAR-T BCMA
VRT-1891Vertex PharmaPhase 1KRASG12CPRMT5i
TixarelsinVertex PharmaPhase 1ALKRAS(ON)i
PemitapinarofBeiGeneApprovedKRASG12CWRNi