← Pipeline|416-1749

416-1749

Preclinical
Source: Trial-derived·Trials: 1
Modality
Gene Editing
MOA
STINGag
Target
HER2
Pathway
NF-κB
MDS
Development Pipeline
Preclinical
Oct 2018
Mar 2029
PreclinicalCurrent
NCT04693378
1,625 pts·MDS
2018-102029-03·Terminated
1,625 total pts1 indication
Phase 1
Phase 2
Phase 3
NDA/BLA
Approved
CompletedCurrentUpcoming
Catalysts (1)
2029-03-062.9y awayInterim· MDS
Trial Timeline
Q42019Q2Q3Q42020Q2Q3Q42021Q2Q3Q42022Q2Q3Q42023Q2Q3Q42024Q2Q3Q42025Q2Q3Q42026Q2Q3Q42027Q2Q3Q42028Q2Q3Q42029Q2
Preclinical
Termina…
Catalysts
Interim
2029-03-06 · 2.9y away
MDS
Terminated|StartCompletionToday
Trials (1)
NCTPhaseIndicationStatusNEP
NCT04693378PreclinicalMDSTerminated1625PFS
Competitors (10)
DrugCompanyPhaseTargetMOA
RHH-5389RochePreclinicalRETSTINGag
GozesotorasibBristol-Myers SquibbNDA/BLAHER2IL-13i
SNY-5894SanofiApprovedCFTRSTINGag
SNY-4496SanofiPhase 2/3CD3STINGag
SNY-5783SanofiPhase 1/2METSTINGag
DSN-1421Daiichi SankyoPhase 3Nectin-4STINGag
GIL-4361Gilead SciencesPreclinicalPCSK9STINGag
VRT-4938Vertex PharmaPreclinicalHER2CDK4/6i
INC-5849IncytePhase 2PCSK9STINGag
MiritinibNeurocrinePhase 3TIGITSTINGag