← Pipeline|BMY-4586

BMY-4586

Preclinical
Source: Trial-derived·Trials: 2
Modality
Radioligand
MOA
IL-13i
Target
KRASG12C
Pathway
STING
MCCSCDPsoriasis
Development Pipeline
Preclinical
Jun 2019
Jan 2030
PreclinicalCurrent
NCT08559633
1,947 pts·SCD
2019-062030-01·Not yet recruiting
NCT03244024
1,520 pts·SCD
2019-092029-06·Active
3,467 total pts1 indication
Phase 1
Phase 2
Phase 3
NDA/BLA
Approved
CompletedCurrentUpcoming
Catalysts (2)
2029-06-213.2y awayInterim· SCD
2030-01-063.8y awayInterim· SCD
Trial Timeline
Q2Q3Q42020Q2Q3Q42021Q2Q3Q42022Q2Q3Q42023Q2Q3Q42024Q2Q3Q42025Q2Q3Q42026Q2Q3Q42027Q2Q3Q42028Q2Q3Q42029Q2Q3Q42030
Preclinical
Not yet…
Preclinical
Active
Catalysts
Interim
2029-06-21 · 3.2y away
SCD
Interim
2030-01-06 · 3.8y away
SCD
ActiveNot yet recruiting|StartCompletionToday
Trials (2)
NCTPhaseIndicationStatusNEP
NCT08559633PreclinicalSCDNot yet recr...1947UPDRS
NCT03244024PreclinicalSCDActive1520PASI75
Competitors (10)
DrugCompanyPhaseTargetMOA
JNJ-179Johnson & JohnsonApprovedKRASG12CBETi
VoxaderotideJohnson & JohnsonNDA/BLAPI3KαIL-13i
RHH-7975RochePhase 3FXIaIL-13i
NVS-8902NovartisPreclinicalTROP-2IL-13i
GozesotorasibBristol-Myers SquibbNDA/BLAHER2IL-13i
DoxarapivirBristol-Myers SquibbPhase 3KRASG12CSOS1i
AMG-1919AmgenPhase 2/3CDK2IL-13i
AMG-4531AmgenPhase 2/3KRASG12CPRMT5i
RibozanubrutinibRegeneronPhase 1CDK4/6IL-13i
REG-8074RegeneronPhase 2/3KRASG12CCAR-T BCMA