← Pipeline|Kemalemzoparlimab

Kemalemzoparlimab

Phase 2
DTI-7975
Source: Trial-derived·Trials: 2
Modality
ASO
MOA
Cl18.2
Target
WEE1
Pathway
Notch
Pompe
Development Pipeline
Preclinical
~Oct 2014
~Jan 2016
Phase 1
~Apr 2016
~Jul 2017
Phase 2
Oct 2017
Aug 2025
Phase 2Current
NCT07985379
1,540 pts·Pompe
2023-072025-08·Active
NCT04584381
2,642 pts·Pompe
2017-10TBD·Terminated
4,182 total pts1 indication
Phase 3
NDA/BLA
Approved
CompletedCurrentUpcoming
Catalysts (2)
2025-08-167mo agoPh2 Data· Pompe
2026-04-081w awayEnrollment Complete· Pompe
Trial Timeline
Q42018Q2Q3Q42019Q2Q3Q42020Q2Q3Q42021Q2Q3Q42022Q2Q3Q42023Q2Q3Q42024Q2Q3Q42025Q2Q3Q42026Q2
P2
Termina…
P2
Active
Catalysts
Ph2 Data
2025-08-16 · 7mo ago
Pompe
Enrollment Complete
2026-04-08 · 1w away
Pompe
ActiveTerminated|StartCompletionToday
Trials (2)
NCTPhaseIndicationStatusNEP
NCT07985379Phase 2PompeActive15406MWD
NCT04584381Phase 2PompeTerminated2642CR
Competitors (10)
DrugCompanyPhaseTargetMOA
ZorivorutinibBristol-Myers SquibbApprovedDLL3Cl18.2
TAK-2403TakedaPhase 2WEE1BTKi
SovacapivasertibAmgenPhase 3WEE1ALKi
ElrarapivirRegeneronPhase 1GIP-RCl18.2
FixaglumideGenmabPhase 2/3WEE1KIF18Ai
HAL-9635HalozymePhase 2/3EZH2Cl18.2
SovarasimodHalozymePhase 1/2WEE1Anti-Tau
VKT-6548Viking TherapeuticsPhase 2/3PD-L1Cl18.2
TiratapinarofIntelliaNDA/BLAAPOC3Cl18.2
BemavorutinibAcadia PharmaPhase 1/2WEE1CD47i