Peptide Targets (27)
Biological targets and receptors relevant to peptide therapeutics.
| Target | Full Name | Family | Pathway | Peptides ↓ | Main DB |
|---|---|---|---|---|---|
| GLP-1R | Glucagon-Like Peptide 1 Receptor | GPCR | Incretin | 13 | ✓ |
| GnRH-R | Gonadotropin-Releasing Hormone Receptor | GPCR | HPG Axis | 6 | |
| GIP-R | Glucose-Dependent Insulinotropic Polypeptide Receptor | GPCR | Incretin | 4 | ✓ |
| MC4R | Melanocortin 4 Receptor | GPCR | Melanocortin | 4 | |
| GHS-R | Growth Hormone Secretagogue Receptor | GPCR | Ghrelin | 4 | |
| SSTR2 | Somatostatin Receptor Type 2 | GPCR | Somatostatin | 3 | |
| AMYR | Amylin Receptor | GPCR | Glucose Metabolism | 3 | |
| GHRH-R | Growth Hormone Releasing Hormone Receptor | GPCR | GHRH | 3 | |
| PTH1R | Parathyroid Hormone 1 Receptor | GPCR | Calcium Homeostasis | 2 | |
| GC-C | Guanylate Cyclase C | Enzyme | cGMP Signaling | 2 | |
| V2R | Vasopressin V2 Receptor | GPCR | Water Balance | 2 | |
| OTR | Oxytocin Receptor | GPCR | Neuroendocrine | 2 | |
| NK1R | Neurokinin 1 Receptor | GPCR | Nociception | 2 | |
| Proteasome 20S | 20S Proteasome Complex | Enzyme | Proteasome | 2 | |
| CTR | Calcitonin Receptor | GPCR | Calcium Homeostasis | 2 | |
| N-type Ca | N-Type Calcium Channel | Ion Channel | Pain Signaling | 2 | |
| SSTR5 | Somatostatin Receptor Type 5 | GPCR | Somatostatin | 1 | |
| CaSR | Calcium-Sensing Receptor | GPCR | Calcium Homeostasis | 1 | |
| NPR-A | Natriuretic Peptide Receptor A | Enzyme | Natriuretic | 1 | |
| Integrin αIIbβ3 | Glycoprotein IIb/IIIa | Receptor Tyrosine Kinase | Coagulation | 1 | |
| KISS1R | Kisspeptin Receptor | GPCR | HPG Axis | 1 | |
| Thrombin | Thrombin (Factor IIa) | Enzyme | Coagulation | 1 | |
| gp41 | HIV-1 Envelope Glycoprotein 41 | Receptor Tyrosine Kinase | Viral Entry | 1 | |
| AT1R | Angiotensin II Type 1 Receptor | GPCR | RAAS | 1 | |
| VPAC1 | Vasoactive Intestinal Peptide Receptor 1 | GPCR | VIP Signaling | 1 | |
| CGRP-R | Calcitonin Gene-Related Peptide Receptor | GPCR | Pain Signaling | 0 | ✓ |
| ETR-A | Endothelin Receptor Type A | GPCR | Vasoconstriction | 0 |